Different worlds and different styles is what would make it so interesting. The point of this isn't to think of ways it wouldn't work because they're on different networks. We're just having fun with the imagination.
Original Cindy is only one of the coolest characters ever! Okay, basically she's gay, that's why I said she could be with Willow.😛
Oooo, and I got another couple that could be fun to see: Clark from Smallville and Buffy; just imagine what the babies would look like...
How about Xander and Jen from Dawson's Creek, or Rory from Gilmore Girls with Connor. Actually, anybody with Connor is just wrong, 'cause with him being a loser.