It's kind of a love/hate thing for me with Conan.
Conan's does tend to slip into that cruel humour a little to hard sometimes. Sometimes the humour just isn't there, so all you're left with is cruel. That can look pretty ugly.
I don't like talk-show host, opening monologue humour in general. It's just too "fill in the blanksy" for me. Once you see the joke set up, you pretty much know what the punchline is going to be:
J Lo -- Big Butt Joke
J Lo & Ben -- Bad movie joke
Anna Nicole -- Trashy woman or fat joke
Bush -- stupid person joke
Monica Lewinsky -- Oral sex joke
R Kelly -- child molester joke
and so on...
On the other hand I like Conan's wacky, off the wall, you never know what's going to happen next stuff, when it works.
I love that bit he does sometimes when a celebrity appears on a television screen with a comic talking behind it. That bit splits my sides sometimes.
Also... If I can see Eliza Dushku every once in a while in a cute little red, Kilt skirt talking with a Bostonian accent, well that's cool too.